Some significant historical events that occurred on March 27 include:
- In 1964, the Great Alaskan Earthquake, the most powerful earthquake recorded in North American history, struck Alaska with a magnitude of 9.2. - In 1977, the Tenerife airport disaster occurred, where two Boeing 747 jumbo jets collided on the runway at Los Rodeos Airport in the Canary Islands, resulting in 583 fatalities. - In 1998, the Food and Drug Administration (FDA) approved Viagra, the first oral treatment for erectile dysfunction.